产品货号：
Z16170
中文名称：
FOXO4抗体
英文名称：
Anti-FOXO4 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-FOXO4 Antibody |
| 指标别名 | AFX;AFX1;forkhead box O4;Forkhead box protein O4;FOXO4;MLLT7 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,ICC,IF |
| 基因名称 | FOXO4 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | FOXO4 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human FOXO4.The immunogen is located within amino acids 30 - 80 of FOXO4. |
| 计算分子量 | 54kDa |
| 成分 | FOXO4 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | FOXO4 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | FOXO4 is a ubiquitously expressed protein member of a subfamily of the forkhead homeotic gene family of transcription factors and shuttles between the cytoplasm and nucleus.FOXO transcription factors are key players of cell fate decisions,metabolism,stress resistance,tumor suppression and are regulated by growth factors,oxidative stress or nutrient deprivation.In the absence of PI3K/AKT activation,FOXO4 localizes in the nucleus where it functions as a transcription factor.FOXO4 can also be phosphorylated by JNK following induction of reactive oxygen species (ROS),resulting in transcriptional activation and the induction of a negative feedback mechanism to counteract the ROS.It is through this mechanism that FOXO4 is thought to sensitize cancer cells to doxorubicin-mediated toxicity. |
| Uniprot ID | P98177 |
| 基因名全称 | Forkhead box O4 |
| 蛋白名全称 | Forkhead box O4 |
| 推荐稀释比 | FOXO4 antibody can be used for detection of FOXO4 by Western blot at 0.5 ～ 1μg/mL.Antibody can also be used for immunocytochemistry starting at 10μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples and Immunocytochemistry in human samples.All other applications and species not yet tested. |
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